Body Protection Compound 157

Overview

BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide corresponding to a stable fragment of a gastric protective protein originally isolated from human gastric juice. It is one of the most extensively studied research peptides in the tissue-repair literature, with several hundred published preclinical studies examining its effects across musculoskeletal, gastrointestinal, and vascular research models. Peptide Factory supplies BPC-157 as a lyophilized powder for laboratory research.

Research Background

The BPC-157 sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) was identified as a stable, protease-resistant fragment of the parent BPC protein. Research groups, most notably at the University of Zagreb, have used rodent models extensively to characterize its effects on angiogenesis, nitric oxide signaling, and growth factor pathways implicated in tissue repair processes.

Studied Applications

Preclinical research on BPC-157 has examined:

• Gastrointestinal protection research — rodent models of induced gastric and intestinal lesions have been used to study mucosal protective effects and healing rate of experimentally induced ulcers.
• Musculoskeletal repair research — tendon, ligament, and muscle injury models in animal research have examined BPC-157’s relationship to fibroblast activity and collagen organization during the healing process.
• Angiogenesis and vascular research — in vitro and in vivo models have investigated BPC-157’s interaction with the VEGFR2 pathway and nitric oxide synthase (NOS) expression.

These are laboratory and animal-model findings; BPC-157 has not been approved for human therapeutic use, and no dosing or administration guidance is provided here.

Storage & Handling

Store lyophilized BPC-157 at -20°C, protected from light and moisture. See our storage and handling guidance for reconstitution best practices.

References

• Sikiric, P. et al. “Pentadecapeptide BPC 157 and its effects on gastrointestinal tract healing.” Preclinical peptide research literature.
• Seiwerth, S. et al. Stable gastric pentadecapeptide BPC 157 and angiogenesis research.
• Chang, C. H. et al. Tendon-to-bone healing research models with BPC-157.

For Research Use Only — Not for Human Consumption.